Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25715827 | 0.83 | KDR (0.42) | FGFR3FGFR2ABL1FGFR1PLK4 | |
| SCHEMBL25715809 | 0.82 | PIK3CD (0.36) | ADKFGFR3MEN1KMT2AABL1 | |
| SCHEMBL25715555 | 0.75 | SRC (0.41) | APPFGFR3MEN1KMT2AABL1 | |
| SCHEMBL25557797 | 0.69 | FGFR2 (0.39) | FGFR3FGFR2ABL1FGFR1CSF1R | |
| SCHEMBL25715611 | 0.67 | TNK2 (0.38) | FGFR3MEN1KMT2AABL1FGFR1 | |
| SCHEMBL25714868 | 0.67 | KDR (0.39) | FGFR3ABL1FGFR1PLK4AURKA | |
| SCHEMBL25557808 | 0.67 | FGFR2 (0.41) | FGFR3FGFR2ABL1FGFR1KDR | |
| SCHEMBL25715685 | 0.65 | PIK3CD (0.43) | FGFR3MEN1KMT2AABL1FGFR1 | |
| SCHEMBL25715554 | 0.65 | SRC (0.42) | ABL1LCKSRCTNK2EGLN2 | |
| SCHEMBL23337052 | 0.62 | ACVRL1 (0.48) | FGFR3FGFR2FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104035-A1 | SUBSTITUTED MONOCYCLIC OR BICYCLIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 英矽智能科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |