Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864496 | 0.77 | HTR1D (0.42) | IDH1HTR1DHTR1BTHRATHRB | |
| SCHEMBL28637900 | 0.70 | SHBG (0.48) | HTR1DHTR1BTHRATHRBSHBG | |
| SCHEMBL24095004 | 0.68 | CYP1A2 (0.41) | PRSS1PRSS2PRSS3 | |
| SCHEMBL19266040 | 0.67 | TAAR1 (0.52) | MAPK8 | |
| SCHEMBL24899309 | 0.66 | ALDH1A1 (0.38) | IDH1MAPK8PRSS1PRSS2C1S | |
| SCHEMBL8964742 | 0.66 | ALDH1A1 (0.38) | IDH1MAPK8PRSS1PRSS2C1S | |
| SCHEMBL24386036 | 0.65 | IDO1 (0.47) | MAPK8 | |
| SCHEMBL5215140 | 0.65 | HTT (0.47) | MAPK8PRSS1PRSS2C1SPRSS3 | |
| SCHEMBL3588189 | 0.65 | IDH1 (0.46) | IDH1SHBG | |
| SCHEMBL19594797 | 0.64 | HRH3 (0.40) | HTR1DHTR1BPRSS1PRSS2C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107412-A1 | POLYMER CONJUGATED THYROINTEGRIN ANTAGONISTS | NANOPHARMACEUTICALS LLC (US) | 2023-06-15 | — | — | WO | disclosed |