Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1316919 | 0.83 | HTR1D (0.48) | HTR1DHTR1BHRH3RAPGEF4CYP11B1 | |
| SCHEMBL23269933 | 0.81 | RAPGEF4 (0.44) | HTR1DHTR1BIDH1HRH3RAPGEF4 | |
| SCHEMBL28637900 | 0.81 | SHBG (0.48) | HTR1DHTR1BRAPGEF4ALDH1A1NR3C1 | |
| SCHEMBL3588189 | 0.80 | IDH1 (0.46) | IDH1CYP11B1CYP11B2ALDH1A1TSHR | |
| SCHEMBL7819859 | 0.78 | CALM1 (0.48) | HTR1DHTR1BIDH1ALDH1A1TSHR | |
| SCHEMBL18557216 | 0.78 | ALDH1A1 (0.44) | HTR1DHTR1BIDH1RAPGEF4ALDH1A1 | |
| SCHEMBL25718436 | 0.77 | IDH1 (0.33) | HTR1DHTR1BIDH1THRATHRB | |
| SCHEMBL15799777 | 0.75 | THRB (0.57) | IDH1RAPGEF4ALDH1A1NR3C1PGR | |
| SCHEMBL28817887 | 0.75 | KMT2A (0.51) | HTR1DHTR1BCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL3690305 | 0.74 | ALDH1A1 (0.44) | IDH1HRH3RAPGEF4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414160-B2 | Process for producing aromatic compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-08-19 | — | — | US | disclosed |
| US-20060106261-A1 | Process for producing aromatic compounds | ISHII YASUTAKA | 2006-05-18 | — | — | US | disclosed |
| EP-1342711-A2 | Process for producing aromatic compounds | Daicel Chemical Industries, Ltd. (JP) | 2003-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106261-A1 | Process for producing aromatic compounds | PAH, HPD, HAO2 | HTR1D 199/4885HTR1B 403/4885IDH1 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.