Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 3/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | CD81 | P60033 | 1/20 | 0.30 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25722755 | 0.89 | PTPN1 (0.45) | PTPN1ALOX5AKR1B10AKR1B1PTPN2 | |
| SCHEMBL25722764 | 0.83 | PTPN1 (0.44) | PTPN1ALOX5AKR1B10AKR1B1PTPN2 | |
| SCHEMBL25723083 | 0.78 | PTPN1 (0.48) | PTPN1ALOX5AKR1B10AKR1B1PTPN2 | |
| SCHEMBL25723050 | 0.69 | PTPN1 (0.55) | PTPN1ALOX5AKR1B10AKR1B1USP2 | |
| SCHEMBL25722822 | 0.66 | PTPN1 (0.59) | PTPN1ALOX5AKR1B10AKR1B1USP2 | |
| SCHEMBL25722752 | 0.65 | PTPN1 (0.57) | PTPN1ALOX5AKR1B10AKR1B1USP2 | |
| SCHEMBL25723089 | 0.60 | ALOX5 (0.54) | PTPN1ALOX5AKR1B10AKR1B1USP2 | |
| SCHEMBL25725092 | 0.59 | PTPN1 (0.44) | PTPN1ALOX5AKR1B10AKR1B1USP2 | |
| SCHEMBL25722821 | 0.58 | — | — | |
| SCHEMBL4324523 | 0.57 | PTPN1 (0.68) | PTPN1ALOX5AKR1B10AKR1B1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159436-A1 | APPLICATIONS OF AMIDE ANALOGS OF TRITERPENES IN CURES OF CANCER AND OTHER DISEASES | PACIFIC ARROW LTD (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159436-A1 | APPLICATIONS OF AMIDE ANALOGS OF TRITERPENES IN CURES OF CANCER AND OTHER DISEASES | UACA, BRDT, FLT3 | PTPN1 3361/4885ALOX5 250/4885AKR1B10 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.