SCHEMBL2832396

SCHEMBL2832396

Nc1c(N)c(Br)c2nsnc2c1Br

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
APAF1 O14727 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
THRB P10828 1/20 0.36
NR4A1 P22736 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
PTPN11 Q06124 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12321816 0.86 MEN1 (0.31) MAPTMEN1KMT2A
SCHEMBL18217203 0.78
SCHEMBL24484539 0.71 MAPT (0.41) MAPTMEN1KMT2APTPN11KDM4E
SCHEMBL15275808 0.71 MAPT (0.47) MAPTMEN1KMT2AAPAF1ALDH1A1
SCHEMBL5655492 0.71 MEN1 (0.32) MAPTMEN1KMT2A
SCHEMBL15032498 0.67 MAPT (0.43) MAPTMEN1KMT2AAPAF1ALDH1A1
SCHEMBL13387379 0.65 MAPT (0.35) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL257288 0.65
SCHEMBL17755560 0.65
SCHEMBL31512660 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119588420-B Based on thiadiazole quinoxaline-benzene preparation method of bithiophene photocatalyst 江苏索普化工股份有限公司 2025-05-13 CN claimed
CN-119588420-A Based on thiadiazole quinoxaline-benzene preparation method of bithiophene photocatalyst 江苏索普化工股份有限公司 2025-03-11 CN claimed
CN-119591619-A Camphor-based fluorescent probe capable of specifically distinguishing different biological thiols, and preparation method and application thereof 江苏食品药品职业技术学院 2025-03-11 CN claimed
CN-117263958-A Fluorescent probe based on camphor derivative and preparation method and application thereof 江苏食品药品职业技术学院 2023-12-22 CN claimed
CN-116375984-A Water-soluble conjugated high-molecular polymer and preparation method thereof 西京学院 2023-07-04 CN claimed
CN-113563366-B Azacycloacene compound and preparation method thereof 阜阳欣奕华材料科技有限公司 2023-02-28 CN claimed
CN-113663731-B Preparation method and application of FL @ MOF composite photocatalyst 西北大学 2022-08-26 CN claimed
CN-113663731-A Preparation method and application of FL @ MOF composite photocatalyst 西北大学 2021-11-19 CN claimed
US-12583863-B2 Synthetically modifiable ion channels UNIVERSITY OF WYOMING (US) 2026-03-24 US disclosed
CN-119588420-B Based on thiadiazole quinoxaline-benzene preparation method of bithiophene photocatalyst 江苏索普化工股份有限公司 2025-05-13 CN disclosed
CN-119591619-A Camphor-based fluorescent probe capable of specifically distinguishing different biological thiols, and preparation method and application thereof 江苏食品药品职业技术学院 2025-03-11 CN disclosed
CN-119588420-A Based on thiadiazole quinoxaline-benzene preparation method of bithiophene photocatalyst 江苏索普化工股份有限公司 2025-03-11 CN disclosed
CN-116023633-B Donor-acceptor electrochromic polymer, preparation method thereof and polymer film 中国人民解放军96901部队25分队 2025-01-14 CN disclosed
CN-115926119-B Electrochromic polymer capable of absorbing in broadband, preparation method of electrochromic polymer and electrochromic film 中国人民解放军96901部队25分队 2024-10-15 CN disclosed
US-20120205596-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
WO-2011119239-A1 WATER SOLUBLE NEAR INFRARED SENSING POLYMERS WITH LOW BAND GAPS HITACHI CHEMICAL CO., LTD. (JP) 2011-09-29 WO disclosed
US-7842758-B2 Conjugated materials featuring proquinoidal units THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2010-11-30 US disclosed
US-20090221762-A1 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS THE TRUSSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-09-03 US disclosed
WO-2007081991-A9 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS UNIV PENNSYLVANIA (US) 2007-09-07 WO disclosed
WO-2007081991-A2 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221762-A1 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS PML, ILK, PARG MAPT 83/4885MEN1 226/4885KMT2A 2698/4885
US-12583863-B2 Synthetically modifiable ion channels HCN4, HCN3, HCN2 MAPT 2810/4885MEN1 1357/4885KMT2A 1012/4885
US-20120205596-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 MAPT 3843/4885MEN1 2256/4885KMT2A 2742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.