SCHEMBL257314

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL257700	0.88	TP53 (0.34)	TP53MAPTKMT2APOLBKDM4E
	SCHEMBL257309	0.87	TP53 (0.39)	TP53MAPTKMT2APOLBKDM4E
	SCHEMBL257382	0.82	TP53 (0.53)	TP53MAPTKMT2APOLBALDH1A1
	SCHEMBL15020811	0.80	TP53 (0.43)	TP53MAPTKMT2AKDM4EALDH1A1
	SCHEMBL257519	0.80	MAPT (0.40)	TP53MAPTKMT2APOLBKDM4E
	SCHEMBL15020909	0.77	PDE10A (0.34)	TP53ADORA2AADORA1
	SCHEMBL21177370	0.75	MAPT (0.45)	TP53MAPTKMT2AKDM4EALDH1A1
	SCHEMBL257316	0.73	POLB (0.61)	TP53STAT1MAPTKMT2APOLB
	SCHEMBL257503	0.73	ALDH1A1 (0.50)	TP53MAPTKMT2APOLBKDM4E
	SCHEMBL13516316	0.72	MAPT (0.66)	TP53MAPTKMT2APOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.