Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25731598 | 0.94 | MGLL (0.53) | MGLLPDE4BTRPV3HPGDSGPR119 | |
| SCHEMBL25731609 | 0.92 | GPR119 (0.50) | MGLLGPR119KDM4EMAPTTHRB | |
| SCHEMBL25731611 | 0.81 | MGLL (0.51) | MGLLPDE4BKDM4E | |
| SCHEMBL25304381 | 0.81 | POLB (0.52) | MGLLTRPV3 | |
| SCHEMBL29638842 | 0.80 | MGLL (0.50) | MGLLGPR119USP30 | |
| SCHEMBL29946091 | 0.80 | KDM4E (0.50) | TRPV3GPR119KDM4EMAPTTHRB | |
| SCHEMBL21137324 | 0.80 | MGLL (0.50) | MGLLGPR119USP30 | |
| SCHEMBL6520490 | 0.79 | HSD11B1 (0.55) | PDE4BTRPV3HPGDSGPR119KDM4E | |
| SCHEMBL25731552 | 0.79 | MGLL (0.47) | MGLLGPR119KDM4EHTT | |
| SCHEMBL25258845 | 0.79 | USP30 (0.43) | PDE4BHPGDSGPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |