Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30212958 | 0.81 | METAP2 (0.47) | METAP2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2658449 | 0.81 | IDO1 (0.47) | IDO1METAP2RAB9ANPC1KDM4E | |
| SCHEMBL24028067 | 0.81 | METAP2 (0.47) | METAP2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL7918782 | 0.79 | KMT2A (0.52) | IDO1METAP2RAB9ANPC1KDM4E | |
| SCHEMBL31402293 | 0.78 | DYRK1A (0.44) | ALDH1A1 | |
| SCHEMBL26251811 | 0.78 | IDO1 (0.45) | IDO1METAP2RAB9ANPC1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28862485 | 0.76 | AOC3 (0.43) | METAP2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL2629317 | 0.74 | KMT2A (0.62) | IDO1METAP2RAB9ANPC1KDM4E | |
| SCHEMBL23685707 | 0.73 | RAB9A (0.55) | IDO1METAP2RAB9ANPC1KDM4E | |
| SCHEMBL12264968 | 0.72 | RAB9A (0.54) | IDO1METAP2RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |