Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688533 | 0.79 | KIF11 (0.46) | CYP19A1KIF11GAAHSD17B10MTNR1A | |
| SCHEMBL338965 | 0.74 | MTNR1A (0.44) | MTNR1A | |
| SCHEMBL23480266 | 0.69 | CYP19A1 (0.49) | LMNACYP19A1GAAMAPTMAP1LC3B | |
| SCHEMBL21986022 | 0.69 | ALOX15 (0.39) | KIF11ALOX15MTNR1A | |
| SCHEMBL23716873 | 0.69 | ALOX15 (0.39) | KIF11ALOX15MTNR1A | |
| SCHEMBL23716860 | 0.69 | ALOX15 (0.39) | KIF11ALOX15MTNR1A | |
| SCHEMBL4685390 | 0.68 | KIF11 (0.41) | KIF11MTNR1A | |
| SCHEMBL4685386 | 0.68 | KIF11 (0.41) | KIF11MTNR1A | |
| SCHEMBL6124100 | 0.67 | CYP19A1 (0.77) | CYP19A1GAAMAPTMAP1LC3BKMT2A | |
| SCHEMBL8473758 | 0.64 | PTPRC (0.42) | LMNAMAPTKMT2AMEN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122754-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING GB13, GB22 AND HIMGALINE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |