Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25733559 | 0.90 | GPR119 (0.43) | PIK3CDPIK3CAGPR119HDAC3HDAC4 | |
| SCHEMBL31730879 | 0.90 | GPR119 (0.43) | PIK3CDPIK3CAGPR119HDAC3HDAC4 | |
| SCHEMBL31730923 | 0.89 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3R1GPR119HDAC3 | |
| SCHEMBL25733410 | 0.89 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3R1GPR119HDAC3 | |
| SCHEMBL25229681 | 0.88 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3R1GPR119HDAC3 | |
| SCHEMBL31730992 | 0.84 | KDM4E (0.35) | PIK3CDPIK3CAHDAC3HDAC4HDAC1 | |
| SCHEMBL30254584 | 0.82 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3R1GPR119HDAC3 | |
| SCHEMBL25733434 | 0.82 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3R1GPR119HDAC3 | |
| SCHEMBL31730977 | 0.81 | KDM4E (0.38) | PIK3CDPIK3CAHDAC3HDAC4HDAC1 | |
| SCHEMBL25733537 | 0.81 | KDM4E (0.38) | PIK3CDPIK3CAHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | KINETA INC (US) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | TDP1, TDP2, PIKFYVE | PIK3CD 138/4885PIK3CA 132/4885PIK3R1 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.