Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293793 | 0.88 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP3A4CYP2C19TTR | |
| SCHEMBL2593397 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL5673785 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL5065594 | 0.87 | CYP1A2 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL2593349 | 0.87 | CYP1A2 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL6588549 | 0.87 | CYP1A2 (0.47) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL221788 | 0.85 | MTNR1A (0.53) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL19181007 | 0.84 | CHEK1 (0.61) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL704754 | 0.83 | TTR (0.64) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 | |
| SCHEMBL29750606 | 0.83 | TTR (0.64) | ALDH1A1CYP1A2CYP3A4CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143250-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. | 2023-05-11 | — | — | US | disclosed |
| CN-101723841-B | Preparation method of 2-amino-5-alkoxy propiophenone | UNIV EAST CHINA NORMAL | 2012-03-07 | — | — | CN | disclosed |
| CN-101723841-A | Preparation method of 2-amino-5-alkoxy propiophenone | UNIV EAST CHINA NORMAL | 2010-06-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143250-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | HSD17B1, HSD17B13, HSD17B3 | ALDH1A1 125/4885CYP1A2 83/4885CYP3A4 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.