Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2572937 | 1.00 | CES2 (0.50) | CES2CES1CA2PPARGPPARD | |
| Acetic Acid SCHEMBL27734142 | 1.00 | CES2 (0.50) | CES2CES1CA2PPARGPPARD | |
| Acetic Acid SCHEMBL27659112 | 1.00 | CES2 (0.50) | CES2CES1CA2PPARGPPARD | |
| Acetic Acid SCHEMBL10615890 | 1.00 | CES2 (0.50) | CES2CES1CA2PPARGPPARD | |
| Acetic Acid SCHEMBL674467 | 0.90 | CES1 (0.46) | CES2CES1CA2GPR84ALDH1A1 | |
| SCHEMBL11345899 | 0.88 | CES2 (0.48) | CES2CES1CA2PPARGPPARD | |
| Octanoic Acid SCHEMBL18420626 | 0.84 | FABP3 (0.62) | CES2CES1GPR84FABP3CA1 | |
| Dodecanoate SCHEMBL6212245 | 0.84 | FABP3 (0.62) | CES2CES1GPR84FABP3CA1 | |
| Fumaric Acid SCHEMBL1579070 | 0.84 | CES2 (0.44) | CES2CES1CA2FABP3 | |
| Fumaric Acid SCHEMBL1579076 | 0.84 | CES2 (0.44) | CES2CES1CA2FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884837-B2 | Scratch and mar resistant automotive coatings | BASF COATINGS GMBH (DE) | 2024-01-30 | — | — | US | disclosed |
| EP-3456746-B1 | TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE | BRIDGESTONE CORP (JP) | 2023-04-19 | — | — | EP | disclosed |
| EP-3655451-B1 | LOW TEMPERATURE CURING 1K BASECOAT AND METHOD TO COAT A SUBSTRATE WITH THE 1K BASECOAT | BASF COATINGS GMBH (DE) | 2023-04-12 | — | — | EP | disclosed |
| US-11583890-B2 | Low temperature curing 1K basecoat and method to coat a substrate with the 1K basecoat | BASF COATINGS GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| CN-110891993-B | Low temperature curing 1K basecoat and method for coating a substrate with a 1K basecoat | 巴斯夫涂料有限公司 | 2022-11-22 | — | — | CN | disclosed |
| US-11459483-B2 | Low temperature cure coating formed via polarity-facilitated catalyst migration between layers in a double layer curing mechanism | BASF COATINGS GMBH (DE) | 2022-10-04 | — | — | US | disclosed |
| CN-110945085-B | Low temperature cured coatings formed by polarity-promoted catalyst migration between layers in a two-layer cure mechanism | 巴斯夫涂料有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-109476811-B | One-part low temperature cure coating formed via a dual layer cure mechanism | 巴斯夫涂料有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-20210371697-A1 | Scratch and Mar Resistant Automotive Coatings | BASF COATINGS GMBH (DE) | 2021-12-02 | — | — | US | disclosed |
| US-20210371693-A1 | TWO-COMPONENT (2K) CLEARCOAT AND METHOD TO COAT A SUBSTRATE WITH THE TWO-COMPONENT (2K) CLEARCOAT HAVING ENHANCED VISUAL APPEARANCE | BASF CORPORATION | 2021-12-02 | — | — | US | disclosed |
| EP-1798218-A1 | MONOMER COMPOUND, PROCESS FOR PRODUCING THE SAME, POLYMER THEREOF, AND WATER-BASED CURABLE COMPOSITION | KANSAI PAINT CO., LTD. (JP) | 2007-06-20 | — | — | EP | disclosed |
| US-7070859-B2 | Acrylic resin composition organosiloxane resin composition and laminate comprising the same | TEIJIN CHEMICALS, LTD. (JP) | 2006-07-04 | — | — | US | disclosed |
| US-20060124462-A1 | Method of coating with lead-free electrodeposition coating composition and coated article | HONDA MOTOR CO., LTD. (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1516722-A1 | ACRYLIC RESIN COMPOSITION, ORGANOSILOXANE RESIN COMPOSITION AND LAMINATES MADE BY USING THEM | Teijin Chemicals, Ltd. (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-20040247878-A1 | Acrylic resin composition organosiloxane resin composition and laminate comprising the same | TEIJIN CHEMICALS LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| WO-2004078856-A1 | LEAD-FREE ELECTRODEPOSITION COATING COMPOSITON AND COATED ARTICLE | HONDA MOTOR CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004078857-A1 | METHOD OF COATING WITH LEAD-FREE ELECTRODEPOSITION COATING COMPOSITION AND COATED ARTICLE | HONDA MOTOR CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |
| EP-0073835-B1 | PROCESS FOR PRODUCING POLYURETHANE POLYMER | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |
| US-4404352-A | ORGANOTIN COMPOUNDS AS CATALYST AND AMINES TO GIVE CURED COATINGS WITH PARTIALLY BLOCKED ISOCYANATES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0073835-A1 | PROCESS FOR PRODUCING POLYURETHANE POLYMER | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1983-03-16 | — | — | EP | disclosed |