Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2572937 | 1.00 | CES2 (0.50) | CES2CES1CA2PPARGPPARD | |
| Acetic Acid SCHEMBL27659112 | 1.00 | CES2 (0.50) | CES2CES1CA2PPARGPPARD | |
| Acetic Acid SCHEMBL2573452 | 1.00 | CES2 (0.50) | CES2CES1CA2PPARGPPARD | |
| Acetic Acid SCHEMBL10615890 | 1.00 | CES2 (0.50) | CES2CES1CA2PPARGPPARD | |
| Acetic Acid SCHEMBL674467 | 0.90 | CES1 (0.46) | CES2CES1CA2GPR84ALDH1A1 | |
| SCHEMBL11345899 | 0.88 | CES2 (0.48) | CES2CES1CA2PPARGPPARD | |
| Octanoic Acid SCHEMBL18420626 | 0.84 | FABP3 (0.62) | CES2CES1GPR84FABP3CA1 | |
| Dodecanoate SCHEMBL6212245 | 0.84 | FABP3 (0.62) | CES2CES1GPR84FABP3CA1 | |
| Fumaric Acid SCHEMBL1579070 | 0.84 | CES2 (0.44) | CES2CES1CA2FABP3 | |
| Fumaric Acid SCHEMBL1579076 | 0.84 | CES2 (0.44) | CES2CES1CA2FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101339959-B | Thin film transistor and preparation of semiconductor film | UNIV TSINGHUA | 2012-03-14 | — | — | CN | claimed |
| CN-101339959-A | Thin film transistor and preparation of semiconductor film | UNIV TSINGHUA (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-101339959-B | Thin film transistor and preparation of semiconductor film | UNIV TSINGHUA | 2012-03-14 | — | — | CN | disclosed |
| CN-101339959-A | Thin film transistor and preparation of semiconductor film | UNIV TSINGHUA (CN) | 2009-01-07 | — | — | CN | disclosed |