Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27734142 | 0.90 | CES2 (0.50) | CES1CA1CES2GPR84ALDH1A1 | |
| Acetic Acid SCHEMBL2572937 | 0.90 | CES2 (0.50) | CES1CA1CES2GPR84ALDH1A1 | |
| Acetic Acid SCHEMBL10615890 | 0.90 | CES2 (0.50) | CES1CA1CES2GPR84ALDH1A1 | |
| Acetic Acid SCHEMBL2573452 | 0.90 | CES2 (0.50) | CES1CA1CES2GPR84ALDH1A1 | |
| Acetic Acid SCHEMBL27659112 | 0.90 | CES2 (0.50) | CES1CA1CES2GPR84ALDH1A1 | |
| Oxalic Acid SCHEMBL1401946 | 0.89 | CA1 (0.46) | CES1CA1CES2FFAR3HDAC3 | |
| Methacrylic Acid SCHEMBL6883217 | 0.85 | TSHR (0.39) | CES1CA1CES2GPR84ALDH1A1 | |
| Acetic Acid SCHEMBL10894448 | 0.85 | CA1 (0.53) | CES1CA1CES2FFAR3HDAC3 | |
| Thioglycolic Acid SCHEMBL7700486 | 0.82 | CA1 (0.46) | CES1CA1CES2FFAR3HDAC3 | |
| SCHEMBL6072819 | 0.82 | CA1 (0.50) | CES1CA1CES2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119177107-B | Glue for SPC board and preparation method thereof | 有行鲨鱼（上海）科技股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-117625062-A | Double-point process of adhesive lining based on polyurethane foundation paste | 江苏高泓新材料有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-104448267-B | The preparation method of solid epoxy toughening polyester | 南京林业大学 | 2019-01-15 | — | — | CN | claimed |
| CN-107266658-A | The polyurethane elastomer of a kind of main chain containing ferrocene and preparation method thereof | 苏州大学 | 2017-10-20 | — | — | CN | claimed |
| CN-105199092-B | A kind of transformer alicyclic ring based epoxy resin hyper-branched polyester toughener preparation method | 安徽互感器有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-105199092-A | Preparation method of alicyclic epoxy resin hyperbranched polyester flexibilizer for mutual inductors | ANHUI INSTR TRANSFORMER CO LTD | 2015-12-30 | — | — | CN | claimed |
| CN-104448267-A | Method for preparing solid epoxy resin toughened polyester | UNIV NANJING FORESTRY | 2015-03-25 | — | — | CN | claimed |
| US-5688890-A | Thermoplastic polyurethane composition | KURARAY CO., LTD. (JP) | 1997-11-18 | — | — | US | claimed |
| US-4555542-A | WITH ORGANOTIN COMPOUND, AND AMIDE CONTAINING PHENOLIC ANTIOXIDANT | TORAY INDUSTRIES, INC. (JP) | 1985-11-26 | — | — | US | claimed |
| EP-0058503-B1 | POLYESTER-POLYETHER COPOLYMER COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 1985-10-09 | — | — | EP | claimed |
| EP-0058503-A1 | Polyester-polyether copolymer composition | TORAY INDUSTRIES, INC. (JP) | 1982-08-25 | — | — | EP | claimed |
| US-4322519-A | USING AN ORGANOTIN COMPOUND CATALYST | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-03-30 | — | — | US | claimed |
| JP-5302007-A | — | — | None | — | — | JP | disclosed |
| JP-2030765-A | — | — | None | — | — | JP | disclosed |
| JP-11080608-A | — | — | None | — | — | JP | disclosed |
| JP-6248060-A | — | — | None | — | — | JP | disclosed |
| US-4066397-A | CURING POLYETHER-URETHANE | MILLIKEN RESEARCH CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4056488-A | SYNTHETIC AMORPHOUS SILICAS OF PREDETERMINED PORE DISTRIBUTION, METHOD OF PRODUCING SAME | MOBIL OIL CORPORATION (US) | 1977-11-01 | — | — | US | disclosed |
| US-4003825-A | CRACKING CATALYSTS | MOBIL OIL CORPORATION (US) | 1977-01-18 | — | — | US | disclosed |
| US-3983055-A | Synthetic amorphous silicas of predetermined pore distribution method of producing same | MOBIL OIL CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |