Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.44 |
| ▸ | NAMPT | P43490 | 10/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25271466 | 0.88 | CHRNB2 (0.36) | KEAP1NFE2L2NAMPTCHRNB2CHRNB4 | |
| SCHEMBL25642262 | 0.88 | CHRNB2 (0.36) | KEAP1NFE2L2NAMPTCHRNB2CHRNB4 | |
| SCHEMBL25735190 | 0.84 | NAMPT (0.46) | KEAP1NFE2L2NAMPTCCR3 | |
| SCHEMBL25735218 | 0.84 | NAMPT (0.46) | KEAP1NFE2L2NAMPTCCR3 | |
| SCHEMBL25735151 | 0.84 | NAMPT (0.46) | KEAP1NFE2L2NAMPTCCR3 | |
| SCHEMBL25735170 | 0.82 | KEAP1 (0.42) | KEAP1NFE2L2NAMPTCCR3 | |
| SCHEMBL25735186 | 0.82 | NAMPT (0.56) | KEAP1NFE2L2NAMPTCCR3 | |
| SCHEMBL25735181 | 0.82 | NAMPT (0.56) | KEAP1NFE2L2NAMPTCCR3 | |
| SCHEMBL25735223 | 0.82 | NAMPT (0.56) | KEAP1NFE2L2NAMPTCCR3 | |
| SCHEMBL25735147 | 0.82 | NAMPT (0.56) | KEAP1NFE2L2NAMPTCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192651-A1 | Pyrrolidine Derivative and Use Thereof | WANG, ZHEMING (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192651-A1 | Pyrrolidine Derivative and Use Thereof | WANG, ZHEMING (CN) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192651-A1 | Pyrrolidine Derivative and Use Thereof | NAMPT, NAPRT, NNMT | KEAP1 2515/4885NFE2L2 3310/4885NAMPT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.