Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25735699 | 0.80 | KMT2A (0.53) | KMT2AHSD11B1APOBEC3GNR1I2TAS2R14 | |
| SCHEMBL25736043 | 0.80 | KMT2A (0.56) | KMT2AHSD11B1APOBEC3GNR1I2TAS2R14 | |
| SCHEMBL3899893 | 0.80 | KMT2A (0.56) | KMT2AHSD11B1APOBEC3GMAPTKEAP1 | |
| SCHEMBL25735706 | 0.80 | KMT2A (0.56) | KMT2AHSD11B1APOBEC3GNR1I2TAS2R14 | |
| SCHEMBL16964148 | 0.79 | KMT2A (0.49) | KMT2AHSD11B1CCR5TAS2R14MAPT | |
| SCHEMBL25735702 | 0.77 | NR1I2 (0.58) | KMT2AHSD11B1APOBEC3GNR1I2MAPT | |
| SCHEMBL25702587 | 0.77 | KMT2A (0.53) | KMT2AHSD11B1APOBEC3GNR1I2TAS2R14 | |
| SCHEMBL12077041 | 0.76 | CCR5 (0.61) | KMT2AHSD11B1APOBEC3GNR1I2CCR5 | |
| SCHEMBL25712464 | 0.75 | KMT2A (0.51) | KMT2AHSD11B1APOBEC3GNR1I2TAS2R14 | |
| SCHEMBL25735703 | 0.74 | NR1I2 (0.54) | KMT2AHSD11B1NR1I2TAS2R14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | ERBB2, ACP1, TK1 | KMT2A 1636/4885HSD11B1 4168/4885APOBEC3G 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.