Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 10/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25735706 | 0.89 | KMT2A (0.56) | KMT2AKEAP1NFE2L2MAPK1HSD11B1 | |
| SCHEMBL25702587 | 0.86 | KMT2A (0.53) | KMT2AKEAP1NFE2L2MAPK1HSD11B1 | |
| SCHEMBL25736043 | 0.85 | KMT2A (0.56) | KMT2AHSD11B1MAPTAPOBEC3G | |
| SCHEMBL25735703 | 0.83 | NR1I2 (0.54) | KMT2AMAPK1HSD11B1MAPT | |
| SCHEMBL25735699 | 0.82 | KMT2A (0.53) | KMT2AKEAP1NFE2L2MAPK1HSD11B1 | |
| SCHEMBL25712464 | 0.81 | KMT2A (0.51) | KMT2AKEAP1NFE2L2MAPK1HSD11B1 | |
| SCHEMBL3899542 | 0.80 | KMT2A (0.47) | KMT2AMAPK1HSD11B1MAPT | |
| SCHEMBL25702589 | 0.80 | RAB9A (0.51) | KMT2AHSD11B1MAPTAPOBEC3G | |
| SCHEMBL25735698 | 0.80 | KMT2A (0.50) | KMT2AKEAP1NFE2L2MAPK1HSD11B1 | |
| SCHEMBL25702584 | 0.80 | KMT2A (0.50) | KMT2AKEAP1NFE2L2MAPK1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1788429-B1 | Method of making a lithographic printing plate | AGFA GRAPHICS NV (BE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007057346-A2 | METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2007-05-24 | — | — | WO | disclosed |
| EP-1788429-A1 | Method of making a lithographic printing plate | Agfa Graphics N.V. (BE) | 2007-05-23 | — | — | EP | disclosed |