Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 9/20 | 0.53 |
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PAH | P00439 | 1/20 | 0.43 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.33 |
| ▸ | FPGS | Q05932 | 2/20 | 0.33 |
| ▸ | GART | P22102 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10161108 | 0.83 | NOS1 (0.51) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL584982 | 0.78 | NOS1 (0.64) | NOS1NOS3NOS2CASP7HSD17B10 | |
| Hydrochloric Acid SCHEMBL16741181 | 0.76 | NOS1 (0.62) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL2044797 | 0.70 | NOS1 (0.78) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL9248337 | 0.69 | NOS1 (0.72) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL4649231 | 0.69 | NOS1 (0.72) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL4649233 | 0.69 | NOS1 (0.72) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL10615701 | 0.68 | NOS1 (0.71) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL188413 | 0.68 | NOS1 (0.56) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL156195 | 0.68 | KDM4E (0.57) | NOS1NOS3NOS2CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | ERBB2, ACP1, TK1 | NOS1 3916/4885NOS3 3941/4885NOS2 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.