Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25740947 | 1.00 | OPRM1 (0.47) | OPRM1OPRL1TMEM97CARM1PRMT6 | |
| SCHEMBL13634464 | 0.90 | OPRM1 (0.49) | OPRM1OPRL1TMEM97CARM1PRMT6 | |
| SCHEMBL13634472 | 0.90 | OPRM1 (0.49) | OPRM1OPRL1TMEM97CARM1PRMT6 | |
| SCHEMBL13927260 | 0.90 | OPRM1 (0.49) | OPRM1OPRL1TMEM97CARM1PRMT6 | |
| SCHEMBL12683078 | 0.84 | CTSL (0.50) | OPRM1OPRL1TMEM97CARM1PRMT6 | |
| SCHEMBL12683224 | 0.84 | CTSL (0.50) | OPRM1OPRL1TMEM97CARM1PRMT6 | |
| SCHEMBL8370443 | 0.84 | CTSL (0.50) | OPRM1OPRL1TMEM97CARM1PRMT6 | |
| SCHEMBL3660170 | 0.84 | OPRM1 (0.56) | OPRM1OPRL1TMEM97CARM1PRMT6 | |
| SCHEMBL24620048 | 0.83 | NAAA (0.47) | SIGMAR1HRH3ALDH1A1 | |
| Methyl Alcohol SCHEMBL10438266 | 0.82 | OPRM1 (0.55) | OPRM1OPRL1TMEM97CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |