Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970447 | 0.84 | RXFP1 (0.50) | MLYCDLMNACA12CA1CA2 | |
| SCHEMBL709048 | 0.84 | ABCG2 (0.50) | LMNACYP3A4TSHRTPMTMAPT | |
| SCHEMBL15100737 | 0.82 | MLYCD (0.41) | MLYCDLMNACA12CA1CA2 | |
| SCHEMBL26709446 | 0.78 | LMNA (0.42) | MLYCDLMNACA12CA1CA2 | |
| SCHEMBL31346688 | 0.78 | ALOX5 (0.51) | MLYCDLMNACA12CA1CA2 | |
| SCHEMBL15197098 | 0.77 | MLYCD (0.37) | MLYCDLMNACA12CA1CA2 | |
| SCHEMBL31346684 | 0.77 | MEN1 (0.49) | LMNACA12CA1CA2CA4 | |
| SCHEMBL13664923 | 0.76 | CYP1A2 (0.45) | MLYCDLMNACA12CA1CA2 | |
| SCHEMBL708366 | 0.76 | CLK1 (0.47) | MLYCDTSHRCLK1DYRK1ADYRK1B | |
| SCHEMBL24488761 | 0.75 | LMNA (0.67) | LMNACA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029942-A1 | CYCLIC AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |