Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25745964 | 0.76 | MAOB (0.45) | MAOBHDAC6NAMPT | |
| SCHEMBL25745961 | 0.75 | LMNA (0.48) | MAOBHDAC6NAMPT | |
| SCHEMBL25745959 | 0.73 | NAMPT (0.68) | HDAC6NPC1RAB9ANAMPT | |
| SCHEMBL936546 | 0.73 | SCD (0.47) | MAOBMAOANPC1RAB9AL3MBTL1 | |
| SCHEMBL25745885 | 0.73 | NAMPT (0.48) | MAOBHDAC6NPC1RAB9ANAMPT | |
| SCHEMBL2943870 | 0.71 | KIT (0.79) | KITMAPK14LCKSRC | |
| SCHEMBL25745892 | 0.71 | NAMPT (0.41) | MAOBHDAC6NAMPT | |
| SCHEMBL937257 | 0.70 | SCD (0.52) | MAOBMAOA | |
| SCHEMBL2952365 | 0.69 | KIT (1.00) | KITMAPK14LCKSRC | |
| SCHEMBL31004385 | 0.69 | KIT (1.00) | KITMAPK14LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781554-B1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FOER MEDICINSK FORSKNING (SE) | 2023-06-28 | — | — | EP | disclosed |