Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 8/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25745961 | 0.83 | LMNA (0.48) | MAOBGCGRNAMPTHDAC6 | |
| SCHEMBL25745959 | 0.79 | NAMPT (0.68) | NAMPTHDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL25745949 | 0.76 | KIT (0.53) | MAOBNAMPTHDAC6 | |
| SCHEMBL25745892 | 0.76 | NAMPT (0.41) | MAOBGCGRNAMPTHDAC3HDAC1 | |
| SCHEMBL25745885 | 0.76 | NAMPT (0.48) | MAOBNAMPTHDAC3HDAC1HDAC8 | |
| SCHEMBL21379406 | 0.75 | NAMPT (0.48) | MAOBGCGRNAMPTHDAC3HDAC1 | |
| SCHEMBL22341942 | 0.69 | P4HTM (0.46) | MAOBGCGRNAMPTHDAC3HDAC1 | |
| SCHEMBL27482073 | 0.67 | GCGR (0.50) | MAOBGCGR | |
| SCHEMBL16785423 | 0.67 | KCNQ3 (0.60) | — | |
| SCHEMBL20255231 | 0.67 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781554-B1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FOER MEDICINSK FORSKNING (SE) | 2023-06-28 | — | — | EP | disclosed |