Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16633588 | 0.86 | ESR1 (0.43) | CYP1A2OPRM1 | |
| SCHEMBL16633288 | 0.80 | NPSR1 (0.45) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1270470 | 0.79 | ALOX5 (0.51) | CYP1A2ALOX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2197076 | 0.79 | ALOX5 (0.51) | CYP1A2ALOX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2576026 | 0.79 | ALOX5 (0.51) | CYP1A2ALOX5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16634014 | 0.79 | DAGLA (0.41) | MEN1KMT2A | |
| SCHEMBL8155052 | 0.78 | SMN1; SMN2 (0.40) | CYP1A2ALOX5MEN1KMT2ARAB9A | |
| SCHEMBL16633048 | 0.76 | CYP2C9 (0.41) | CYP1A2MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6825359 | 0.76 | SMN1; SMN2 (0.39) | CYP1A2ALOX5MEN1KMT2ARAB9A | |
| SCHEMBL16243710 | 0.76 | LMNA (0.42) | CYP1A2OPRM1OPRD1ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123419-A1 | TRYCYCLIC COMPOUNDS AND PBK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2011-10-06 | — | — | WO | disclosed |