Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155052 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2CYP1A2ALOX5LMNAALDH1A1 | |
| SCHEMBL17076396 | 0.85 | ATM (0.40) | ALOX5LMNACYP2D6MEN1KMT2A | |
| SCHEMBL17076397 | 0.85 | ATM (0.40) | ALOX5LMNACYP2D6MEN1KMT2A | |
| SCHEMBL16632962 | 0.83 | CES2 (0.41) | CYP2D6CYP2C9HIF1A | |
| SCHEMBL2576026 | 0.80 | ALOX5 (0.51) | SMN1; SMN2CYP1A2ALOX5LMNAALDH1A1 | |
| SCHEMBL1270470 | 0.80 | ALOX5 (0.51) | SMN1; SMN2CYP1A2ALOX5LMNAALDH1A1 | |
| SCHEMBL2197076 | 0.80 | ALOX5 (0.51) | SMN1; SMN2CYP1A2ALOX5LMNAALDH1A1 | |
| SCHEMBL26931937 | 0.79 | RARB (0.39) | CYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL16563726 | 0.78 | TRPV1 (0.40) | ALDH1A1KMT2A | |
| SCHEMBL16243710 | 0.77 | LMNA (0.42) | SMN1; SMN2CYP1A2ALOX5LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052363-A1 | OXAZOLIDINONES USED AS ANTIVIRAL AGENTS, IN PARTICULAR FOR FIGHTING AGAINST CYTOMEGALOVIRUS | BAYER HEALTHCARE AG (DE) | 2004-06-24 | — | — | WO | disclosed |