SCHEMBL2574724

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3346512	0.82	KDM4E (0.42)	GCGRLMNABRS3KDM4EALDH1A1
	SCHEMBL3346515	0.81	DRD2 (0.44)	GCGRLMNABRS3KDM4EALDH1A1
	SCHEMBL15648532	0.78	KDM4E (0.49)	GCGRLMNAKDM4EALDH1A1MAPK1
	SCHEMBL3779844	0.77	TRPA1 (0.39)	KDM4EMAPK1
	SCHEMBL3775578	0.74	CYP3A4 (0.40)	LMNA
	SCHEMBL2576380	0.74	MME (0.43)	LMNA
	SCHEMBL3346518	0.73	PPARG (0.41)	GCGRLMNABRS3KDM4EALDH1A1
	SCHEMBL20630517	0.72	SLC7A5 (0.54)	LMNAKDM4EALDH1A1MAPK1NOTUM
	SCHEMBL20630516	0.72	SLC7A5 (0.54)	LMNAKDM4EALDH1A1MAPK1NOTUM
	SCHEMBL27801748	0.72	DRD2 (0.42)	GCGRLMNAKDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.