Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.59 |
| ▸ | DNM2 | P50570 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340473 | 0.86 | ESR1 (0.47) | KCNH3DNM2KMT2AESR1ESR2 | |
| SCHEMBL9342560 | 0.84 | KCNH3 (0.49) | KCNH3DNM2KMT2AF2RL1 | |
| SCHEMBL514975 | 0.81 | KCNH3 (0.63) | KCNH3DNM2KMT2AESR1ESR2 | |
| SCHEMBL11500110 | 0.80 | KCNH3 (0.54) | KCNH3DNM2KMT2AESR1ESR2 | |
| SCHEMBL3299537 | 0.79 | KMT2A (0.67) | KCNH3DNM2KMT2ASLC29A1 | |
| SCHEMBL14441528 | 0.79 | KMT2A (0.67) | KCNH3DNM2KMT2ASLC29A1 | |
| SCHEMBL14441519 | 0.79 | KMT2A (0.67) | KCNH3DNM2KMT2ASLC29A1 | |
| SCHEMBL3298621 | 0.79 | KMT2A (0.67) | KCNH3DNM2KMT2ASLC29A1 | |
| SCHEMBL1032562 | 0.79 | KMT2A (0.67) | KCNH3DNM2KMT2ASLC29A1 | |
| SCHEMBL3298608 | 0.79 | KMT2A (0.67) | KCNH3DNM2KMT2ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598182-B2 | Insecticidal pyrimidinyl aryl hyrdrazones | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | claimed |
| US-20110319615-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2011-12-29 | — | — | US | claimed |
| EP-2197853-B1 | INSECTICIDAL PYRIMIDINYL ARYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2011-11-09 | — | — | EP | claimed |
| EP-2197853-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYDRAZONES | Dow AgroSciences LLC (US) | 2010-06-23 | — | — | EP | claimed |
| WO-2009048751-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-16 | — | — | WO | claimed |
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DDT, HELZ, HPD | KCNH3 1141/4885DNM2 297/4885KMT2A 1767/4885 |
| US-20110319615-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DDT, HELZ, HPD | KCNH3 1141/4885DNM2 297/4885KMT2A 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.