Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189618 | 0.86 | MAPT (0.44) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL25748397 | 0.84 | MAPT (0.42) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL31077747 | 0.84 | MAPT (0.41) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL25748377 | 0.84 | SMN1; SMN2 (0.41) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL25748392 | 0.83 | MAPT (0.41) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL30483756 | 0.83 | APP (0.42) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL25748387 | 0.82 | MAPT (0.40) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL25748215 | 0.79 | PTPN1 (0.42) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL25748342 | 0.78 | SMN1; SMN2 (0.42) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL10532503 | 0.77 | LTA4H (0.54) | SMN1; SMN2PTGER1LTA4HPLA2G2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115166-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |