SCHEMBL30483756

SCHEMBL30483756

CCCN(CCC)C(=O)C(=O)c1c[nH]c2c(C)ccc(OCc3ccccc3)c12

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.42
▸ MAPT P10636 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ TRPM8 Q7Z2W7 1/20 0.38
▸ FFAR4 Q5NUL3 1/20 0.38
▸ PTPN1 P18031 1/20 0.38
▸ HTR2A P28223 1/20 0.37
▸ EDNRA P25101 1/20 0.36
▸ ALOX5 P09917 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ JAK2 O60674 1/20 0.36
▸ JAK3 P52333 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25748397 0.92 MAPT (0.42) APPMAPTCYP2C9CYP2C19SMN1; SMN2
SCHEMBL25748387 0.91 MAPT (0.40) APPMAPTCYP2C9CYP2C19SMN1; SMN2
SCHEMBL27189618 0.87 MAPT (0.44) APPMAPTCYP2C9CYP2C19SMN1; SMN2
SCHEMBL25748377 0.87 SMN1; SMN2 (0.41) APPMAPTCYP2C9CYP2C19SMN1; SMN2
SCHEMBL31077747 0.84 MAPT (0.41) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL25748392 0.84 MAPT (0.41) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL25748376 0.83 MAPT (0.45) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL25748279 0.82 HTR1D (0.39) SMN1; SMN2MEN1KMT2APTPN1HTR2A
SCHEMBL27189571 0.76 TDP1 (0.40) APPMAPTCYP2C9CYP2C19SMN1; SMN2
SCHEMBL23805270 0.74 HTR2A (0.52) APPSMN1; SMN2MEN1KMT2ATRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101038-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-03-27 — — US disclosed
EP-4452937-A1 COMPOUNDS Psylo Pty Ltd (AU) 2024-10-30 — — EP disclosed
CN-118715204-A Compounds of formula (I) 普赛洛私人有限公司 2024-09-27 — — CN disclosed
WO-2023115166-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101038-A1 COMPOUNDS NLN, SLC18A2, PYGB APP 1141/4885MAPT 139/4885CYP2C9 1232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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