SCHEMBL31077747

SCHEMBL31077747

Cc1ccc(OCc2ccccc2)c2c(C(=O)C(=O)N(C(C)C)C(C)C)c[nH]c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ TRPM8 Q7Z2W7 2/20 0.39
▸ FFAR4 Q5NUL3 1/20 0.38
▸ PTPN1 P18031 1/20 0.38
▸ EDNRA P25101 1/20 0.37
▸ RXRA P19793 1/20 0.36
▸ RXRB P28702 1/20 0.36
▸ RXRG P48443 1/20 0.36
▸ PTGER1 P34995 1/20 0.35
▸ MCL1 Q07820 1/20 0.35
▸ HTR2A P28223 1/20 0.35
▸ FOLH1 Q04609 1/20 0.35
▸ LTA4H P09960 1/20 0.35
▸ PLA2G2A P14555 1/20 0.35
▸ ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25748392 0.91 MAPT (0.41) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL27189618 0.88 MAPT (0.44) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL25748397 0.86 MAPT (0.42) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL25748377 0.85 SMN1; SMN2 (0.41) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL30483756 0.84 APP (0.42) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL25748387 0.84 MAPT (0.40) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL25748376 0.84 MAPT (0.45) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL23805289 0.83 HTR2A (0.51) SMN1; SMN2TRPM8EDNRAPTGER1HTR2A
SCHEMBL31077657 0.81 PTPN1 (0.38) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1
SCHEMBL27189571 0.77 TDP1 (0.40) MAPTCYP2C9CYP2C19SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101038-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-03-27 — — US disclosed
CN-118715204-A Compounds of formula (I) 普赛洛私人有限公司 2024-09-27 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101038-A1 COMPOUNDS NLN, SLC18A2, PYGB MAPT 139/4885CYP2C9 1232/4885CYP2C19 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback