Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.45 |
| ▸ | HTR6 | P50406 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | HTR1F | P30939 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30483738 | 1.00 | MTNR1A (0.45) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL30877278 | 0.89 | MTNR1A (0.43) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL29206392 | 0.89 | MTNR1A (0.43) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL25748622 | 0.89 | MTNR1A (0.43) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL30483757 | 0.89 | MTNR1A (0.43) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL30877224 | 0.88 | HTR6 (0.42) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL29206375 | 0.88 | HTR6 (0.42) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL30877243 | 0.87 | HTR1A (0.59) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL31158591 | 0.86 | MTNR1A (0.44) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 | |
| SCHEMBL29206401 | 0.86 | HTR1A (0.45) | MTNR1AMTNR1BHTR6HTR1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | disclosed |
| WO-2023115166-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |