Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25748676 | 0.87 | ESRRG (0.48) | PRSS1TPSAB1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL25567568 | 0.87 | PRSS1 (0.43) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL21132846 | 0.87 | F13A1 (0.41) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL26192260 | 0.86 | PPARA (0.41) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL25751042 | 0.85 | MEN1 (0.45) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL19592679 | 0.85 | F13A1 (0.44) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL25964314 | 0.82 | PRSS1 (0.46) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL25964144 | 0.82 | PRSS1 (0.43) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL13596297 | 0.82 | F13A1 (0.40) | PRSS1TPSAB1F13A1TGM2TGM1 | |
| SCHEMBL25881500 | 0.81 | L3MBTL1 (0.51) | PRSS1TPSAB1TGM2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685742-B2 | Anti-tumor compound and preparation method and use thereof | DUALITY BIOLOGICS (SUZHOU) CO., LTD. (CN) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685742-B2 | Anti-tumor compound and preparation method and use thereof | RCC2, REN, VHL | PRSS1 1874/4885TPSAB1 532/4885F13A1 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.