Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25962335 | 0.90 | PRSS1 (0.42) | PRSS1TPSAB1ALDH1A1F13A1TGM2 | |
| SCHEMBL25749532 | 0.86 | LMNA (0.46) | PRSS1TPSAB1HPGDKDM4EF13A1 | |
| SCHEMBL13596562 | 0.86 | F13A1 (0.43) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL25964314 | 0.85 | PRSS1 (0.46) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL24760586 | 0.83 | F13A1 (0.41) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL25749356 | 0.82 | PRSS1 (0.41) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL16015346 | 0.82 | PRSS1 (0.48) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL24797627 | 0.81 | PRSS1 (0.45) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL27439043 | 0.81 | PRSS1 (0.48) | PRSS1TPSAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL7367495 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HPGDF13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223318-A1 | ANTITUMOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |