Bromide

Bromide

SCHEMBL2575150

CC[N+](C)(C)c1ccccc1.[AlH2]Br.[Br-]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 4/20 0.52
OPRM1 known ✓ P35372 1/20 0.48
CHRM4 known ✓ P08173 1/20 0.32
CHRM1 known ✓ P11229 1/20 0.32
CHRM3 known ✓ P20309 1/20 0.32
TSHR P16473 1/20 0.48
BLM P54132 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
DNM1 Q05193 1/20 0.32
CHRNB2 P17787 2/20 0.31
CHRNB4 P30926 2/20 0.31
CHRNA3 P32297 2/20 0.31
CHRNA7 P36544 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL3881994 0.93 ACHE (0.57) ACHETSHROPRM1BLMSMN1; SMN2
Bromide SCHEMBL2575151 0.91 ACHE (0.55) ACHETSHROPRM1BLMSMN1; SMN2
Bromide SCHEMBL2575147 0.91 ACHE (0.55) ACHETSHROPRM1BLMSMN1; SMN2
SCHEMBL2954430 0.91 ACHE (0.56) ACHETSHROPRM1BLMSMN1; SMN2
SCHEMBL7553902 0.88 ACHE (0.54) ACHETSHROPRM1BLMSMN1; SMN2
Hydrochloric Acid SCHEMBL11288802 0.88 ACHE (0.57) ACHETSHROPRM1BLMSMN1; SMN2
Water SCHEMBL7548761 0.88 ACHE (0.54) ACHETSHROPRM1BLMSMN1; SMN2
Fluoride Ion SCHEMBL7548962 0.88 ACHE (0.54) ACHETSHROPRM1BLMSMN1; SMN2
SCHEMBL7553904 0.88 ACHE (0.54) ACHETSHROPRM1BLMSMN1; SMN2
SCHEMBL11569379 0.84 ACHE (0.50) ACHETSHROPRM1BLMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110269263-A1 METHOD FOR IMPLANTING IMPURITIES INTO A SUBSTRATE AND METHOD FOR MANUFACTURING A SOLAR CELL USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-11-03 US claimed
US-20110269263-A1 METHOD FOR IMPLANTING IMPURITIES INTO A SUBSTRATE AND METHOD FOR MANUFACTURING A SOLAR CELL USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-11-03 US disclosed