Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.57 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.54 |
| ▸ | CHRM4 known ✓ | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.34 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2575151 | 0.97 | ACHE (0.55) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Bromide SCHEMBL2575147 | 0.97 | ACHE (0.55) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| SCHEMBL2954430 | 0.97 | ACHE (0.56) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| SCHEMBL7553902 | 0.95 | ACHE (0.54) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Water SCHEMBL7548761 | 0.95 | ACHE (0.54) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11288802 | 0.95 | ACHE (0.57) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Fluoride Ion SCHEMBL7548962 | 0.95 | ACHE (0.54) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| SCHEMBL7553904 | 0.95 | ACHE (0.54) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Bromide SCHEMBL2575150 | 0.93 | ACHE (0.52) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| SCHEMBL11569379 | 0.90 | ACHE (0.50) | ACHETSHROPRM1BLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104419944-B | The method that electrochemistry prepares silicon fiml | 韩国原子力研究院 | 2017-06-16 | — | — | CN | claimed |
| US-9291595-B2 | Monitoring method and system of metal ions or oxygen ions applicable to high concentration non-aqueous electrolyte | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2016-03-22 | — | — | US | claimed |
| CN-103308588-B | Method and system for monitoring metal ions or oxygen ions applicable to high-concentration non-aqueous electrolyte | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2015-12-23 | — | — | CN | claimed |
| CN-104419944-A | Electrochemical Preparation Method of Silicon Film | KOREA ATOMIC ENERGY RES | 2015-03-18 | — | — | CN | claimed |
| US-20150050816-A1 | METHOD OF ELECTROCHEMICALLY PREPARING SILICON FILM | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2015-02-19 | — | — | US | claimed |
| US-20130264222-A1 | MONITORING METHOD AND SYSTEM OF METAL IONS OR OXYGEN IONS APPLICABLE TO HIGH CONCENTRATION NON-AQUEOUS ELECTROLYTE | KOREA HYDRO & NUCLEAR POWER CO., LTD. (KR) | 2013-10-10 | — | — | US | claimed |
| CN-103308588-A | Method and system for monitoring metal ions or oxygen ions applicable to high-concentration non-aqueous electrolyte | KOREA HYDRO & NUCLEAR POWER CO | 2013-09-18 | — | — | CN | claimed |
| EP-2683792-B1 | NOVEL ETCHING COMPOSITION | FUJIFILM ELECTRONIC MAT USA INC (US) | 2019-09-25 | — | — | EP | disclosed |
| CN-104419944-B | The method that electrochemistry prepares silicon fiml | 韩国原子力研究院 | 2017-06-16 | — | — | CN | disclosed |
| EP-2807289-B1 | ETCHING COMPOSITION | FUJIFILM ELECTRONIC MATERIALS (US) | 2016-09-21 | — | — | EP | disclosed |
| US-9291595-B2 | Monitoring method and system of metal ions or oxygen ions applicable to high concentration non-aqueous electrolyte | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2016-03-22 | — | — | US | disclosed |
| CN-103308588-B | Method and system for monitoring metal ions or oxygen ions applicable to high-concentration non-aqueous electrolyte | KOREA ATOMIC ENERGY RESEARCH INSTITUTE (KR) | 2015-12-23 | — | — | CN | disclosed |
| US-9200372-B2 | Passivation composition and process | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2015-12-01 | — | — | US | disclosed |
| CN-103308588-A | Method and system for monitoring metal ions or oxygen ions applicable to high-concentration non-aqueous electrolyte | KOREA HYDRO & NUCLEAR POWER CO | 2013-09-18 | — | — | CN | disclosed |
| US-20130122701-A1 | Novel Passivation Composition and Process | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2013-05-16 | — | — | US | disclosed |
| WO-2013059806-A1 | Novel Passivation Composition and Process | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2013-04-25 | — | — | WO | disclosed |
| WO-2012125401-A1 | NOVEL ETCHING COMPOSITION | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2012-09-20 | — | — | WO | disclosed |
| US-20120231632-A1 | Novel Etching Composition | FUJIFILM CORPORATION (JP) | 2012-09-13 | — | — | US | disclosed |
| US-7560585-B2 | Process for preparing (S)- alpha-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-isovalerate | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-07-14 | — | — | US | disclosed |
| US-20060128982-A1 | Process for preparing (S)- alpha-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-isovalerate | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128982-A1 | Process for preparing (S)- alpha-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-isovalerate | PCCA, CHRNE, CHRNB4 | ACHE 1353/4885OPRM1 2792/4885CHRM4 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.