Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | POLD1 | P28340 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751533 | 0.92 | TK1 (0.57) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL24059268 | 0.89 | POLB (0.66) | TK1POLBTYMS | |
| SCHEMBL25751494 | 0.84 | TK1 (0.52) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL25751535 | 0.84 | TK1 (0.52) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL24059013 | 0.83 | TK1 (0.62) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL25696528 | 0.81 | POLB (0.63) | TK1POLBTYMS | |
| SCHEMBL25752755 | 0.81 | POLB (0.63) | TK1POLBTYMS | |
| SCHEMBL25756120 | 0.79 | POLB (0.62) | TK1POLBTYMS | |
| SCHEMBL25756126 | 0.78 | POLB (0.61) | TK1POLBTYMS | |
| SCHEMBL7038209 | 0.78 | TK1 (0.74) | TK1POLBPOLA1POLD1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049218-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |