SCHEMBL25751809

SCHEMBL25751809

c1cc2c(c(-n3c4ccccc4c4ccccc43)c1)Cc1ccc(-n3c4ccccc4c4ccccc43)cc1-2

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 1/20 0.35
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CA6 P23280 2/20 0.32
PNMT P11086 1/20 0.32
DUSP3 P51452 1/20 0.31
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17467403 0.89 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1CA1
SCHEMBL17467399 0.89 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1CA1
SCHEMBL26531390 0.89 KDM4E (0.41) KDM4EATML3MBTL1ALDH1A1CA1
SCHEMBL5028290 0.89 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1
SCHEMBL17052840 0.86 EDNRB (0.33) KDM4EATML3MBTL1ALDH1A1EDNRB
SCHEMBL17676393 0.86 KDM4E (0.34) KDM4EATML3MBTL1ALDH1A1CA1
SCHEMBL17676370 0.86 KDM4E (0.34) KDM4EATML3MBTL1ALDH1A1CA1
SCHEMBL15402268 0.85 PNMT (0.44) KDM4EATML3MBTL1ALDH1A1CA1
SCHEMBL12219217 0.83 KDM4E (0.50) KDM4EATML3MBTL1ALDH1A1DUSP3
SCHEMBL19849205 0.83 KDM4E (0.36) KDM4EATML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-06 US disclosed
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, EPB41L2, CTNNBL1 KDM4E 3122/4885ATM 3445/4885L3MBTL1 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.