Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751888 | 0.83 | HTT (0.30) | — | |
| SCHEMBL25751856 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1POLBTDP1HSD17B10 | |
| SCHEMBL21368401 | 0.75 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL21368402 | 0.75 | — | — | |
| SCHEMBL21367898 | 0.73 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL22515639 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1 | |
| SCHEMBL21375807 | 0.68 | GRM2 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL24738058 | 0.67 | MAPT (0.48) | L3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL31006016 | 0.67 | L3MBTL1 (0.43) | L3MBTL1KDM4EALDH1A1POLBTDP1 | |
| SCHEMBL14445097 | 0.66 | PTGS2 (0.44) | L3MBTL1KDM4EALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122782-A2 | INDOLES, INDAZOLES, AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |