SCHEMBL25751893

SCHEMBL25751893

Nc1cc(Br)ccc1Sc1ccccc1Br

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 4/20 0.42
PDE7B Q9NP56 2/20 0.42
SLC6A4 P31645 11/20 0.41
SLC6A2 P23975 9/20 0.41
SLC6A3 Q01959 5/20 0.41
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5115412 0.85 PDE7A (0.42) PDE7APDE7BSLC6A4SLC6A2LMNA
SCHEMBL24439551 0.82 SLC6A2 (0.56) PDE7APDE7BSLC6A4SLC6A2SLC6A3
SCHEMBL810478 0.79 ALDH1A1 (0.45) PDE7ASLC6A4SLC6A2SLC6A3LMNA
SCHEMBL3998999 0.77 KDM4E (0.71) LMNATDP1KDM4EALDH1A1
SCHEMBL29543575 0.77 LMNA (0.57) PDE7APDE7BLMNATDP1ALDH1A1
SCHEMBL3282096 0.77 LMNA (0.57) PDE7APDE7BLMNATDP1ALDH1A1
SCHEMBL24439562 0.76 SLC6A4 (0.44) PDE7APDE7BSLC6A4SLC6A2SLC6A3
SCHEMBL21862048 0.76 PDE7A (0.43) PDE7APDE7BSLC6A4SLC6A2LMNA
SCHEMBL1645148 0.75 SLC6A4 (0.72) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL488915 0.73 ALDH1A1 (0.47) SLC6A4SLC6A2SLC6A3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-06 US disclosed
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, EPB41L2, CTNNBL1 PDE7A 4621/4885PDE7B 4523/4885SLC6A4 4427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.