SCHEMBL2575215

SCHEMBL2575215

C=C(OCC)c1cnc2nnn(Cc3cccc4cccnc34)c2n1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MET P08581 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1163124 0.82 MET (0.70) MET
SCHEMBL1163238 0.81 MET (0.71) MET
SCHEMBL6521725 0.77 MET (0.50) MET
SCHEMBL2569722 0.73 MET (0.61) MET
SCHEMBL2573902 0.73 PSEN1 (0.47) MET
SCHEMBL2572016 0.73 MET (0.68) MET
SCHEMBL2572670 0.72 MET (0.56) MET
SCHEMBL2572904 0.72 MET (0.49) MET
SCHEMBL2566584 0.71 MET (0.70) MET
SCHEMBL2572265 0.71 MET (0.48) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2018383-B1 TRIAZOLOPYRAZINE DERIVATIVES USEFUL AS ANTI-CANCER AGENTS PFIZER PROD INC (US) 2011-11-09 EP claimed