SCHEMBL25752187

SCHEMBL25752187

CC/C=C\C/C=C\CCCN1CC[N+](C)=C1N=[N+]=[N-]

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 2/20 0.31
ALDH1A1 P00352 1/20 0.31
F7 P08709 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CYP19A1 P11511 1/20 0.31
F3 P13726 1/20 0.31
RXRA P19793 1/20 0.31
PTGS1 P23219 1/20 0.31
PPARG P37231 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
OXER1 Q8TDS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30277658 0.95
SCHEMBL24052362 0.82 MEN1 (0.33) KMT2A
SCHEMBL24059144 0.79 EEF2K (0.36) KMT2A
SCHEMBL24052157 0.79 EEF2K (0.36) KMT2A
SCHEMBL25752203 0.79 EEF2K (0.36) KMT2A
SCHEMBL24059296 0.78 ALDH1A1 (0.34) FABP3ALDH1A1F7ADORA3CYP19A1
SCHEMBL30277372 0.78 MEN1 (0.30) KMT2A
SCHEMBL30277681 0.74 EEF2K (0.34)
SCHEMBL30277540 0.74 EEF2K (0.34)
SCHEMBL25752140 0.68 EEF2K (0.34) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF RNGTT, NSUN2, ALKBH1 FABP3 1427/4885ALDH1A1 1901/4885F7 3565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.