Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.75 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.75 |
| ▸ | CES2 | O00748 | 5/20 | 0.75 |
| ▸ | HPGD | P15428 | 5/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.75 |
| ▸ | IDO1 | P14902 | 5/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | RECQL | P46063 | 4/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.75 |
| ▸ | BLM | P54132 | 4/20 | 0.75 |
| ▸ | CES1 | P23141 | 4/20 | 0.75 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.75 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.75 |
| ▸ | ACHE | P22303 | 3/20 | 0.75 |
| ▸ | TDO2 | P48775 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cryptotanshinone SCHEMBL29387944 | 0.86 | MEN1 (1.00) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| Cryptotanshinone SCHEMBL5940386 | 0.86 | MEN1 (1.00) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| Cryptotanshinone SCHEMBL4126834 | 0.86 | MEN1 (1.00) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| Cryptotanshinone SCHEMBL28181278 | 0.78 | MEN1 (0.83) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| SCHEMBL29405831 | 0.77 | MEN1 (0.83) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| Tanshinone Iib SCHEMBL14417728 | 0.76 | EED (1.00) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| Tanshinone Iib SCHEMBL11945767 | 0.76 | EED (1.00) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| SCHEMBL20457599 | 0.75 | MEN1 (0.51) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| SCHEMBL13883845 | 0.74 | MEN1 (0.74) | MEN1KMT2AALDH1A1TDP1HIF1A | |
| Isotanshinone Iib SCHEMBL30381469 | 0.73 | EED (0.85) | MEN1KMT2AALDH1A1TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | UNIVERSITY OF ROCHESTER | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | MYT1, STAT3, MYC | MEN1 2412/4885KMT2A 901/4885ALDH1A1 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.