SCHEMBL29405831

SCHEMBL29405831

CC1COC2=C1C(=O)c1ccc3c(c1C2=O)CCCC3(C)C

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.83
▸ ALDH1A1 P00352 5/20 0.83
▸ KMT2A Q03164 5/20 0.83
▸ CES2 O00748 5/20 0.83
▸ HPGD P15428 4/20 0.83
▸ HSD17B10 Q99714 4/20 0.83
▸ HIF1A Q16665 4/20 0.83
▸ EPAS1 Q99814 4/20 0.83
▸ CES1 P23141 4/20 0.83
▸ PTPN1 P18031 4/20 0.83
▸ KDM4E B2RXH2 3/20 0.83
▸ MAPT P10636 3/20 0.83
▸ RECQL P46063 3/20 0.83
▸ TDP1 Q9NUW8 3/20 0.83
▸ CYP3A4 P08684 3/20 0.83
▸ BLM P54132 3/20 0.83
▸ IDO1 P14902 3/20 0.83
▸ POLB P06746 2/20 0.83
▸ PTPN6 P29350 2/20 0.83
▸ PTPN11 Q06124 2/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cryptotanshinone SCHEMBL29387944 0.91 MEN1 (1.00) MEN1ALDH1A1KMT2ACES2HPGD
Cryptotanshinone SCHEMBL5940386 0.91 MEN1 (1.00) MEN1ALDH1A1KMT2ACES2HPGD
Cryptotanshinone SCHEMBL4126834 0.91 MEN1 (1.00) MEN1ALDH1A1KMT2ACES2HPGD
Cryptotanshinone SCHEMBL28181278 0.82 MEN1 (0.83) MEN1ALDH1A1KMT2ACES2HPGD
SCHEMBL16421131 0.82 MEN1 (0.57) MEN1ALDH1A1KMT2ACES2HPGD
SCHEMBL25752309 0.77 MEN1 (0.75) MEN1ALDH1A1KMT2ACES2HPGD
SCHEMBL13883845 0.76 MEN1 (0.74) MEN1ALDH1A1KMT2ACES2HPGD
SCHEMBL3332927 0.74 PTPN1 (0.69) MEN1ALDH1A1KMT2ACES2HPGD
SCHEMBL22875593 0.74 PTPN1 (0.69) MEN1ALDH1A1KMT2ACES2HPGD
SCHEMBL13855041 0.73 PTPN1 (0.64) MEN1ALDH1A1KMT2ACES2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116718718-A Qualitative detection method for blood component of musk heart-activating dripping pills 内蒙古康恩贝药业有限公司 2023-09-08 — — CN claimed
CN-113005130-B Tanshinone IIA synthase gene and application thereof 上海辰山植物园 2022-07-08 — — CN claimed
CN-119925445-A Use of natural plant active ingredients for preventing and/or treating ovarian dysfunction diseases 中国科学院生物物理研究所 2025-05-06 — — CN disclosed
CN-119380826-B Chinese patent medicine network pharmacology analysis method and model construction method based on multiscale information entropy 首都医科大学附属北京朝阳医院 2025-04-08 — — CN disclosed
CN-119700855-A Method for extracting total tanshinone from red sage root dregs and application thereof 国药集团宜宾制药有限责任公司 2025-03-28 — — CN disclosed
CN-119431133-A New cryptotanshinone Process for the preparation of ketones 中医药广东省实验室 2025-02-14 — — CN disclosed
CN-119380826-A Chinese patent medicine network pharmacology analysis method and model construction method based on multiscale information entropy 首都医科大学附属北京朝阳医院 2025-01-28 — — CN disclosed
CN-119015340-A Method for separating and purifying tanshinone in red sage root 江西绿天食品有限公司 2024-11-26 — — CN disclosed
EP-3040077-B1 TRADITIONAL CHINESE MEDICINE COMPOSITION TASLY PHARMACEUTICAL GROUP CO (CN) 2024-10-02 — — EP disclosed
EP-3777866-B1 PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF TASLY PHARMACEUTICAL GROUP CO (CN) 2024-08-21 — — EP disclosed
CN-118217325-A Danzhiqing tablet dry extract and preparation method thereof 华润三九医药股份有限公司 2024-06-21 — — CN disclosed
CN-113791154-B Method for identifying chemical components in Xuebijing injection 天津中医药大学 2023-06-23 — — CN disclosed
US-20230147718-A1 COMPOSITION FOR CANCER PREVENTION OR TREATMENT, CONTAINING, AS ACTIVE INGREDIENT, SALVIANOLIC ACID B OR TANSHINONE I GJMEDI (KR) 2023-05-11 — — US disclosed
EP-4154878-A1 APPLICATION OF ACTIVE INGREDIENT OF ROOT OF LIGULILOBE SAGE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF IN PREPARING ANTIVIRAL DRUG Southern Medical University (CN) 2023-03-29 — — EP disclosed
CN-115487280-A Traditional Chinese medicine composition for relieving alcoholism, protecting liver and promoting liver regeneration, preparation and preparation method thereof 浙江中医药大学 2022-12-20 — — CN disclosed
US-11491173-B2 Pharmaceutical composition and application thereof TASLY PHARMACEUTICAL GROUP CO., LTD. (CN) 2022-11-08 — — US disclosed
CN-113318205-B Traditional Chinese medicine composition for treating pleural effusion and pericardial effusion 吉林省中医药科学院(吉林省中医药科学院第一临床医院) 2022-10-28 — — CN disclosed
CN-113005130-B Tanshinone IIA synthase gene and application thereof 上海辰山植物园 2022-07-08 — — CN disclosed
CN-114176171-A Feed additive for increasing yield of poultry and preparation method thereof 河南省奥邦生物科技有限公司 2022-03-15 — — CN disclosed
CN-114085264-A A method for preparing tanshinone IIA extracted from Saviae Miltiorrhizae radix 河南省康华药业股份有限公司 2022-02-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11491173-B2 Pharmaceutical composition and application thereof TNNT2, TNNI3, FABP3 MEN1 4715/4885ALDH1A1 1692/4885KMT2A 4806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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