SCHEMBL25752359

SCHEMBL25752359

Cc1cc2c(=O)c3cc4c(cc3n(-c3ccccc3)c2cc1C)c(=O)c1cc(C)c(C)cc1n4-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAT2A P31153 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
HTT P42858 2/20 0.41
GSK3A P49840 3/20 0.41
GSK3B P49841 3/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 2/20 0.41
NOTUM Q6P988 1/20 0.41
GAA P10253 2/20 0.41
GFER P55789 1/20 0.41
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PGR P06401 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752373 0.86 HTT (0.41) KDM4EL3MBTL1NPC1RAB9AHTT
SCHEMBL25752358 0.83 MAT2A (0.44) KDM4EATML3MBTL1MAT2ANPC1
SCHEMBL85788 0.81 KDM4E (0.63) KDM4EATML3MBTL1GSK3AGSK3B
SCHEMBL29416587 0.81 KDM4E (0.63) KDM4EATML3MBTL1GSK3AGSK3B
SCHEMBL25752396 0.80 NR1H4 (0.46) HTTMAPK1ALDH1A1HPGDSMN1; SMN2
SCHEMBL25752386 0.80 ALDH1A1 (0.46) KDM4EL3MBTL1MAT2AALDH1A1LMNA
SCHEMBL25752410 0.80 MAPT (0.39) KDM4EHTTHPGDLMNASMN1; SMN2
SCHEMBL18054854 0.80 KDM4E (0.67) KDM4EATML3MBTL1NPC1RAB9A
SCHEMBL25752368 0.79 MAT2A (0.45) KDM4EATML3MBTL1MAT2AGSK3A
SCHEMBL12433687 0.79 MAT2A (0.47) KDM4EATML3MBTL1MAT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed