SCHEMBL25752373

SCHEMBL25752373

Cc1ccc(-n2c3cc(C)c(C)cc3c(=O)c3cc4c(cc32)c(=O)c2cc(C)c(C)cc2n4-c2ccc(C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.41
LMNA P02545 3/20 0.41
NOTUM Q6P988 1/20 0.40
POLB P06746 1/20 0.40
F2 P00734 1/20 0.39
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
CTRC Q99895 1/20 0.39
TSHR P16473 4/20 0.39
NPSR1 Q6W5P4 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
KMT2A Q03164 4/20 0.39
GSK3B P49841 2/20 0.39
MEN1 O00255 2/20 0.39
GSK3A P49840 1/20 0.39
KDM4E B2RXH2 4/20 0.38
MAPT P10636 3/20 0.38
GAA P10253 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752370 0.86 HTT (0.41) HTTLMNANOTUMPOLBF2
SCHEMBL25752359 0.86 KDM4E (0.44) HTTLMNANOTUMTSHRSMN1; SMN2
SCHEMBL25752410 0.84 MAPT (0.39) HTTLMNANPSR1SMN1; SMN2KMT2A
SCHEMBL25752396 0.83 NR1H4 (0.46) HTTTSHRNPSR1SMN1; SMN2KMT2A
SCHEMBL25752386 0.83 ALDH1A1 (0.46) LMNAPOLBSMN1; SMN2KMT2AMEN1
SCHEMBL25752369 0.83 P2RX4 (0.51) HTTLMNAPOLBNPSR1SMN1; SMN2
SCHEMBL25752382 0.81 HTT (0.39) HTTLMNANOTUMPOLBF2
SCHEMBL21666906 0.81 POLB (0.42) HTTLMNANOTUMPOLBF2
SCHEMBL25752377 0.80 MGLL (0.37) HTTLMNANOTUMPOLBF2
SCHEMBL25752376 0.80 ALDH1A1 (0.36) HTTLMNANOTUMPOLBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed