SCHEMBL25752382

SCHEMBL25752382

CCc1cc2c(=O)c3cc4c(cc3n(-c3ccc(C)cc3)c2cc1CC)c(=O)c1cc(CC)c(CC)cc1n4-c1ccc(C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
TP53 P04637 1/20 0.39
NPC1 O15118 4/20 0.37
RAB9A P51151 4/20 0.37
CYP2C19 P33261 2/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
POLB P06746 2/20 0.37
PSMD14 O00487 1/20 0.37
RECQL P46063 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ELANE P08246 2/20 0.37
P2RX4 Q99571 1/20 0.36
F2 P00734 1/20 0.36
CTSG P08311 1/20 0.36
CMA1 P23946 1/20 0.36
CTRC Q99895 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752417 0.85 MAPT (0.36) HTTSMN1; SMN2CYP2C19MAPTNPSR1
SCHEMBL25752368 0.85 MAT2A (0.45) SMN1; SMN2CYP2C19CYP1A2CYP2C9POLB
SCHEMBL25752380 0.83 P2RX4 (0.43) HTTSMN1; SMN2TP53NPC1RAB9A
SCHEMBL25752404 0.83 NR1H4 (0.39) HTTSMN1; SMN2NPC1CYP2C19MAPT
SCHEMBL25752392 0.83 TDP1 (0.39) SMN1; SMN2TP53MAPTPOLBRECQL
SCHEMBL25752373 0.81 HTT (0.41) HTTSMN1; SMN2TP53NPC1RAB9A
SCHEMBL25752370 0.81 HTT (0.41) HTTSMN1; SMN2TP53NPC1RAB9A
SCHEMBL25752369 0.79 P2RX4 (0.51) HTTSMN1; SMN2TP53NPC1RAB9A
SCHEMBL25752467 0.77 CRHR1 (0.33) TP53MAPTLMNAMEN1KMT2A
SCHEMBL21666906 0.77 POLB (0.42) HTTSMN1; SMN2TP53NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed