SCHEMBL25752437

SCHEMBL25752437

Cc1ccc2c(c1)c(=O)c1cc3c(cc1n2-c1cc(C(C)(C)C)cc(C(C)(C)C)c1)c(=O)c1ccccc1n3-c1cc(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MARK4 Q96L34 3/20 0.43
P2RX4 Q99571 1/20 0.39
MAPT P10636 5/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
RXFP1 Q9HBX9 2/20 0.38
KMT2A Q03164 2/20 0.38
THRB P10828 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
PGR P06401 1/20 0.37
RORA P35398 1/20 0.37
RORC P51449 1/20 0.37
RORB Q92753 1/20 0.37
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TP53 P04637 2/20 0.36
NTRK1 P04629 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752554 0.92 ALDH1A1 (0.40) P2RX4MAPTKMT2AMEN1NPC1
SCHEMBL25752439 0.88 TSHR (0.32) MARK4P2RX4MAPTPOLBALDH1A1
SCHEMBL13311194 0.81 PPARG (0.46) P2RX4MAPTKMT2APGRRORA
SCHEMBL13833031 0.81 KDM4E (0.53) MARK4P2RX4MAPTSMN1; SMN2RXFP1
SCHEMBL22960147 0.79 CA9 (0.34) MAPTNPC1PGRRORARORC
SCHEMBL25752406 0.79 MAPT (0.46) MARK4P2RX4MAPTSMN1; SMN2KMT2A
SCHEMBL25752369 0.79 P2RX4 (0.51) MARK4P2RX4MAPTSMN1; SMN2RXFP1
SCHEMBL30846089 0.79 KDM4E (0.52) MAPTKMT2AMEN1POLBALDH1A1
SCHEMBL25824814 0.78 MARK4 (0.36) MARK4MAPTKMT2AMEN1NPC1
SCHEMBL25752440 0.78 POLB (0.32) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed