SCHEMBL25752439

SCHEMBL25752439

Cc1ccc2c(=O)c3cc4c(cc3n(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)c2c1)c(=O)c1ccc(C)cc1n4-c1cc(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
CCR9 P51686 1/20 0.32
MARK4 Q96L34 2/20 0.32
P2RX4 Q99571 1/20 0.31
MCL1 Q07820 2/20 0.31
BCL2 P10415 1/20 0.31
MDM2 Q00987 1/20 0.31
MAPT P10636 2/20 0.31
MAPK1 P28482 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
ALDH1A1 P00352 1/20 0.31
NOTUM Q6P988 1/20 0.30
KDM4E B2RXH2 1/20 0.30
APAF1 O14727 1/20 0.30
PKM P14618 1/20 0.30
IDO1 P14902 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CSF1R P07333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752394 0.88 NR1H4 (0.40) TSHRCCR9MCL1BCL2MDM2
SCHEMBL22960147 0.88 CA9 (0.34) MAPTMAPK1NPSR1ALDH1A1NOTUM
SCHEMBL25752437 0.88 MARK4 (0.43) MARK4P2RX4MAPTMAPK1NPSR1
SCHEMBL25752483 0.84 MARK4 (0.33) TSHRCCR9MARK4P2RX4MCL1
SCHEMBL25752554 0.84 ALDH1A1 (0.40) P2RX4MAPTMAPK1NPSR1ALDH1A1
SCHEMBL25752440 0.83 POLB (0.32) NOTUMPOLB
SCHEMBL25752407 0.83 MAPT (0.39) TSHRMARK4P2RX4MAPTNPSR1
SCHEMBL25752411 0.82 MAPT (0.33) TSHRMAPTMAPK1NPSR1ALDH1A1
SCHEMBL25752374 0.82 TSHR (0.40) TSHRP2RX4MAPTMAPK1NPSR1
SCHEMBL25752370 0.81 HTT (0.41) TSHRMARK4P2RX4MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed