SCHEMBL25824814

SCHEMBL25824814

Cc1ccc2c(c1)c(=O)c1cc3c(cc1n2-c1c(C(C)(C)C)cc(C(C)(C)C)cc1C(C)(C)C)c(=O)c1ccc(C)cc1n3-c1c(C(C)(C)C)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MARK4 Q96L34 3/20 0.36
KDM4E B2RXH2 1/20 0.33
APAF1 O14727 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
IDO1 P14902 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
MCL1 Q07820 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CSF1R P07333 1/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
RORA P35398 2/20 0.31
RORC P51449 2/20 0.31
RORB Q92753 2/20 0.31
PGR P06401 1/20 0.30
CCR9 P51686 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752483 0.96 MARK4 (0.33) MARK4MCL1LMNACCR9
SCHEMBL25824818 0.86 PGR (0.35) RAB9ARORARORCRORBPGR
SCHEMBL24702437 0.83 ALDH1A1 (0.39) MARK4KDM4EMAPTMAPK1HTT
SCHEMBL13024147 0.83 KDM4E (0.35) MARK4KDM4EAPAF1MAPTPKM
SCHEMBL25752439 0.81 TSHR (0.32) MARK4KDM4EAPAF1MAPTPKM
SCHEMBL25752484 0.80 POLB (0.32) POLB
SCHEMBL25752486 0.80 GABBR2 (0.31)
SCHEMBL25752489 0.79 PPARG (0.33) RORARORCRORB
SCHEMBL25752490 0.79 PGR (0.32) RORARORCRORBPGR
SCHEMBL18858837 0.78 POLB (0.38) KDM4EAPAF1MAPTPKMIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed