⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22527401 | 0.78 | PIK3CD (0.31) | — | |
| SCHEMBL24847191 | 0.78 | — | — | |
| SCHEMBL23177879 | 0.72 | — | — | |
| SCHEMBL14063426 | 0.69 | LMNA (0.30) | — | |
| SCHEMBL24847332 | 0.68 | MMP1 (0.32) | — | |
| SCHEMBL18513205 | 0.67 | PIK3CD (0.31) | — | |
| SCHEMBL27013740 | 0.67 | MMP8 (0.40) | — | |
| SCHEMBL22664270 | 0.67 | — | — | |
| SCHEMBL15679321 | 0.67 | POLB (0.40) | — | |
| SCHEMBL21557298 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860561-B1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2023-06-21 | — | — | EP | disclosed |