⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68800 | 0.83 | — | — | |
| Bromide SCHEMBL7200266 | 0.82 | — | — | |
| SCHEMBL4437211 | 0.75 | GRIA1 (0.36) | — | |
| Aspartic Acid SCHEMBL5964784 | 0.67 | GRIA1 (0.43) | — | |
| SCHEMBL12481055 | 0.62 | PTGS2 (0.32) | — | |
| SCHEMBL30940446 | 0.60 | TP53 (0.38) | — | |
| SCHEMBL12648359 | 0.60 | GRIA1 (0.49) | — | |
| SCHEMBL5281708 | 0.60 | GRIA1 (0.49) | — | |
| SCHEMBL13319909 | 0.60 | GRIA1 (0.41) | — | |
| SCHEMBL5290687 | 0.60 | GRIA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1978962-A2 | COMPOSITIONS AND METHODS OF TREATMENT USING MODULATORS OF MOTONUERON DISEASES | Kinemed, Inc. (US) | 2008-10-15 | — | — | EP | claimed |
| WO-2007081910-A2 | COMPOSITIONS AND METHODS OF TREATMENT USING MODULATORS OF MOTONUERON DISEASES | KINEMED, INC. (US) | 2007-07-19 | — | — | WO | claimed |
| EP-2382975-A2 | Neurogenesis by modulating angiotensin | Braincells, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |